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Overall, the findings from these two recently completed cardiovascular outcomes trials suggest that the increases in HR associated with the short-acting GLP-1 RA, lixisenatide, or the long-acting GLP-1 RA, liraglutide, do not lead to an increased risk of major adverse cardiac events in patients with T2DM and high cardiovascular risk

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"Mildronate"

A semaglutida e a liraglutida, inclusive, tm aprovao para uso no tratamento da obesidade, mesmo na ausncia de diabetes, graas ao seu impacto significativo na perda ponderal e na melhora dos parmetros metablicos (BURCELIN

The choice between these methods depends on factors such as the specific formulation, patient preference, and healthcare provider recommendations